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It had been shown that protein kinase R (PKR) was activated in the later stages of HSV-1 infection enhancing phosphorylation of eIF-2 (Chou et al., 1995) and inducing phosphorylation of endoplasmic reticulum resident kinase (pERK) (Cheng et al., 2005), thereby inhibiting protein synthesis (Poppers et al., 2000)

Specifically, MS patients have increased plasmatic coagulation, reduced fibrinolysis, hyperreactive platelets, and impaired endothelial thrombo-resistance, increasing the risk for venous and arterial thrombosis (155, 158, 159)

Temperature, light exposure, repeated freeze-thaw cycles, and improper handling remain the primary factors affecting peptide stability

This increases ones risk of major medical conditions such as heart disease and type 2 diabetes