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Currently, several drugs targeting IL-6 signaling such as IL-6 inhibitors (siltuximab, clazakizumab, sirukumab, olokizumab) and IL-6R inhibitors (tocilizumab, sarilumab, levilimab) are available

The possible protective effects of Se against COVID-19 could be due to its role as an essential cofactor in selenoproteins that act to reduce ROS formation, as well as its anti-inflammatory properties by modulating the production of proinflammatory cytokines, since both of them are key mechanisms in the pathophysiology of this infection

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