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3 Results 3.1 Effects of lactic acid bacteria fermentation supernatant on XOD activity The XOD inhibition experiment results in vitro showed that the fermentation supernatant of various lactic acid bacteria had an inhibitory effect on XOD (Figure 2)

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In a recent study, plasma GSH concentrations were decreased by nearly 1.5-fold in inhaled corticosteroid-nave asymptomatic asthmatics compared to healthy controls (284)

This process is mediated by activated DNA methyltransferases (DNMTs) driven by PI3K-AKT signaling, thereby establishing a self-reinforcing oncogenic cycle [19,20,21]