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Statistical analyses All data calculations and statistical analyses were performed using the R software ( version 4.2.2)

Mo X,Lefai e,he L,Cheng X,Zhang X,Chakravarti A,Guo D

Aqua/Water/Eau, Simmondsia Chinensis (Jojoba) Seed Oil, Butyrospermum Parkii (Shea) Butter, Isododecane, Coconut Alkanes, 3-O-Ethyl Ascorbic Acid, Cetearyl Alcohol, Glycerin, Synthetic Beeswax, Dilinoleic Acid/Propanediol Copolymer, Polymethylsilsesquioxane, Cocoyl Proline, Dimethicone Crosspolymer, Pentaerythrityl Tetraisostearate, Tetrahexyldecyl Ascorbate, Ascorbic Acid, Colloidal Gold, Collagen, Glutathione, Citrus Nobilis (Mandarin Orange) Fruit Extract, Citrus Paradisi (Grapefruit) Peel Extract, Glucosyl Hesperidin, Tocopherol, Tamarindus Indica Seed Polysaccharide, Poncirus Trifoliata Fruit Extract, Morus Alba Root Extract, Linoleic Acid, Linolenic Acid, Jojoba Esters, Caprylyl Glycol, Coco-Caprylate/Caprate, Propanediol, Polyglyceryl-3 Cocoate, Polyglyceryl-4 Caprate, Polyglyceryl-6 Caprylate, Polyglyceryl-6 Ricinoleate, Hdi/Trimethylol Hexyllactone Crosspolymer, Polyacrylate-13, Butylene Glycol, Polyglyceryl-3 Stearate, Polysorbate 20, Sodium Citrate, Polyisobutene, Beheneth-5, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Behenyl Alcohol, Sodium Hydroxide, Sorbic Acid, Sorbitan Isostearate, Citric Acid, Sorbitol, Silica, Sodium Benzoate, 1,2-Hexanediol, Xanthan Gum, Phenoxyethanol, Leuconostoc/Radish Root Ferment Filtrate, Mica, Titanium Dioxide (Ci 77891), Iron Oxides (Ci 77491)

When patients express interest in combining these substances, clinicians should conduct a thorough assessment including medical history, current medications, baseline kidney function, and treatment goals