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4.2 Immune cell crosstalk: amplifying the axis cycle Immune cells play a dual role in asthma, both responding to and actively promoting ferroptosis, thereby fueling a cycle of inflammation and cell death

Saunders JE, Cordes SR, Zafereo ME The Small World of Global Otolaryngology

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subsequently, ASC recruits caspase-1 via filamentous CARD-CARD interactions, which solidifies the condensation and reduces their fluidity, ultimately resulting in the formation of mature inflammasomes (Fig