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The combined therapy modulated the brain-derived neurotrophic factor (BDNF), 3-hydroxykynurenine (3-HK), quinolinic acid (QUIN), TNF-, and IL-6 levels, reversing oxidative stress markers in the hippocampus

doi: 10.1016/0003-2697(80)90139-6 35

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108 A randomized controlled trial in 30 healthy volunteers found 200 mg L-theanine daily for four weeks led to improved scores on tests of verbal fluency (the ability to come up with words in specified categories) and executive function, and the improvement was more pronounced in those whose baseline scores were lower