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Injectable therapy is easier to manage when refill planning happens before the last scheduled dose

Carr1 and Silvia Maggini

One serious adverse event (SAE) was reported, one patient after 12 weeks of treatment with l glutamine, presented with disturbed consciousness level, fever, vomiting, right upper quadrant abdominal pain, darkening of his urine with a deepening of his jaundice, and tachypnea, elevated transaminases tenfold with direct hyperbilirubinemia, derangement of kidney functions with abnormal bleeding profile, and metabolic acidosis with a positive anion gap, patient was diagnosed as sickle cell hepatopathy (SCH), admitted to PICU and was managed with supportive measures together, with exchange transfusion

Immunity (2017) 46(4):67589