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Molecular mechanisms underlying the effects of the small molecule AMC-04 on apoptosis: roles of the activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway

Eur J Prev Cardiol 2016;23:1354-62

Participants were instructed to ingest six capsules of the assigned treatment once per day one hour prior to exercise for seven days

[0465] In certain embodiments the linker can be a dipeptide linker, such as a valine- citrulline (val-cit), a phenylalanine-lysine (phe-lys) linker, or maleimidocapronic-valine- citruline-p-aminobenzyloxycarbonyl (vc) linker, a tripeptide linker such as GGG and the like, a tetrapeptide linker such as GGGG (SEQ ID NO:71), a pentapeptide linker such as GGGGS (SEQ ID NO:72), and the like