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Early on, researchers studied the underlying anti-fatigue mechanism of hydrogel and elastomeric systems and demonstrated that when the number of polymer chain entanglements exceeds the cross-linking point, the materials toughness increases and the material exhibits anti-fatigue properties [166, 167]

the second or further nucleotide sequence may encode a protein that provides for fail-safe mechanism that allows curing a subject from the transgenic cells, if deemed necessary

The mitochondrial Ca 2+ uptake is driven by the electrochemical gradient established during oxidative phosphorylation, where the proton concentration gradient across the inner mitochondrial membrane fuels ATP synthesis (Patron et al., 2022