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Another disruptive approach is to inject a hyperosmotic solution (one which has a higher solute concentration than the surrounding cells) into the carotid arteries to open the BBB for a time

Lam PL, Wong RS, Lam KH, Hung LK, Wong MM, Yung LH et al (2020) The role of reactive oxygen species in the biological activity of antimicrobial agents: an updated mini review

109,110 Additionally, antioxidants including vitamins A and C, CoQ10, and -lipoic acid have been suggested to improve behavioral parameters and reduce oxidative stress, mitochondrial dysfunction, and glutamate-induced toxicity in PD

For complex formation we incubated the hTrxR1 mutants with NADPH and the respective hTrx1 mutants