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ARISTADA (aripiprazole lauroxil) covers the complete range of oral aripiprazole for schizophrenia treatment in adults 1-3 ARISTADA Doses Based on Oral Aripiprazole Total Daily Dose 1-3 Aripiprazole lauroxil doses studied in the clinical development program were designed to be consistent with the range of oral aripiprazole doses indicated for the treatment of schizophrenia (10 mg to 30 mg) 3 In conjunction with the first ARISTADA injection, administer one injection of ARISTADA INITIO and one 30 mg dose of oral aripiprazole or continue treatment with oral aripiprazole for 21 consecutive days 1,4 For patients who have never taken aripiprazole, establish tolerability to oral aripiprazole prior to initiating ARISTADA or ARISTADA INITIO 1,4 Dose adjustment considerations ARISTADA INITIO No dose adjustments of ARISTADA INITIO can be made 4 ARISTADA INITIO is only available at a single strength as a single-dose prefilled syringe, so dosage adjustments are not possible

In this study, a 30% decrease in venous plasma and 60% decrease in epithelial lung fluid of asymptomatic HIV-seropositive subject were registered