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Thus, NaBPC157 can be used for the treatment of bone marrow damages induced by irradiation

BPC 157 immune system can improve with inflammation regulation and endothelial tissue protection

INO binds A2A receptors with lower affinity than ADO and preferentially activates ERK1/2 over cAMP signaling ( Targeting the CD38/NAD + axis remains an attractive immunotherapeutic strategy in MM, but the broad expression of CD38 raises concerns about off-target toxicity ( Supplementary Table 1 ), ADA-based degradation ( + surrogates ( Overall, our findings indicate that anti-CD38 therapies engage a dynamic, compartmentalized adenosinergic network in MM, with metabolic adaptations that may influence therapeutic responses

Further validation of the HCC risk stratification value of these findings is warranted and ongoing