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Additionally, they can reduce the expression and activity of key iron uptake proteins such as transferrin receptor, divalent metal transporter 1 (DMT1), and zinc-iron transporters, while also modulating critical regulatory factors including iron-regulated proteins and hypoxia-inducible factor 1 (27)

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In the United States, the FDA regulates drugs for human use, but vendors selling compounds labelled for research purposes only operate in a grey zone that makes straightforward enforcement difficult

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