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Accompanying the loss of AR binding to ARBS1 (and other ARBSs), RT-qPCR analysis using the same paired AD/AI tumors revealed concurrent BCL-2 mRNA upregulation, especially in AR -/lo LAPC9-AI tumors (Fig

TB-500 is the synthetic full-length sequence of thymosin -4, an actin-binding peptide endogenous to most mammalian cell types and originally isolated from calf thymic tissue

The formulation also includes pharmaceutical excipients such as disodium phosphate dihydrate, propylene glycol, phenol, and water for injections to ensure stability and sterility