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The emerging picture is that GHSR-1a is a far broader target than early GH-focused research appreciated and GHRP-6s place in the toolkit has expanded accordingly

10.1016/j.nlm.2010.09.001 Neurobiol

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e , Quantitative mass spectrometry (MS) result showed that depletion of Smurf1 inhibited K48-Nedd8 linkage of PDK1 in Nedd8 R74K HEK293 cells under insulin treatment (n = 5 independent peptides)