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Unlike GLP-1 agonists that reduce appetite or growth hormone peptides that stimulate lipolysis, the compound addresses fat metabolism at the enzymatic level: it removes the molecular governor that locks adipocytes into a low-energy-expenditure state, potentially restoring normal metabolic function in fat tissue where NNMT is overexpressed

In fact, it is probably among the safest medications available: the World Health Organization has included Metformin on its Model List of Essential Medicines, a catalog of some of the safest, most effective and most economical medications in the world

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