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Birsoy and colleagues also found how mitochondrial glutathione drives cancer spread: not by acting as an antioxidantan effect ruled out through multiple experimentsbut by signaling to activate ATF4, a transcription factor that helps cancer cells survive in low-oxygen conditions

Elevated methylmalonic acid is commonly seen in the elderly, either because B12 is poorly absorbed (which may be one of the reasons), or because there is not necessarily a B12 deficiency as such, but rather an alteration in kidney function

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Trace metal contamination in marine fish species: implications for food safety and human health