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However, other studies have challenged the presence or functional relevance of mLOC, arguing instead that lactate is likely to first be converted to pyruvate in the cytosol before being imported into mitochondria via the mitochondrial pyruvate carrier (MPC) [32]

doi: 10.1007/s12035-023-03232-y 169 PanL.SzeY

Flow cytometry analysis HER2-positive cells (HCC1954 cells) were seeded in 6-well plates (2 10 5 cells/ml) and were incubated in humidified air with 5% CO 2 at 37 C for 24 h