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Despite the well-established increase in IFP within breast tumors, our understanding of how breast cancer cells respond to this physical stimulus remains elusive due to the scarcity of reliable in vitro platforms that permit adjustment of pressure independent of changes in pH or the dissolved concentration of gases

NFKB consists of two subunit molecules, p65 and p50, and usually exists as a molecular complex with an inhibitory molecule, , in the cytosol

But tirzepatide also appears to influence metabolism directly