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Description

New hopes for disease modification in Parkinsons disease

TMED4 is a potent activator of NRF2, and loss of TMED4 prevents NRF2 from inducing an antioxidant state within the cell

For instance, alkaloids antofine N -oxide, antofine and tylophorine decreased the pupation and emergence rate of Spodoptera litura larvae (Ge et al., 2015)