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p 0.001) were detected.High ATX expression was associated with poorer tumor grade (p=0.038)and lymphatic metastasis (p=0.024)

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These include molecules and enzymatic regulators involved in the metabolism of glucose, arginine, tryptophan, glutamine, cysteine, lipids, ROS, and AMP-activated protein kinase (AMPK) (28) ( Figure 2 )