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Description

Mathematical modeling of liver injury and dysfunction after acetaminophen overdose: early discrimination between survival and death

Does receptor balance matter?comparing the efficacies of the dual amylin and calcitonin receptor agonists cagrilintide and KBP-336 on metabolic parameters in preclinical models

doi: 10.1097/MCO.0000000000001132

To determine whether dysregulated hepatic glutathione homeostasis and TNF can synergistically contribute to hepatocyte death, we performed cell culture studies using both human hepatoma cells and mouse non-transformed hepatocytes