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10.3390/ph15070854 121 MarroneL.DrexlerH

Burrow H, Prayaga K (2004) Correlated responses in productive and adaptive traits and temperament following selection for growth and heat resistance in tropical beef cattle

In particular, in 43 septic patients with MAS and concomitant disseminated intravascular coagulation, hepatobiliary dysfunction, cytopenias and hyperferritinemia, when compared with placebo, anakinra treatment significantly improved the28-day survival rate (anakinra: 65.4%

Under the iron-rich, ROS-prone conditions characteristic of lesions, this perturbation engages a coordinated program of RCD across intersecting pathwaysnot only ferroptosis but also necroptotic and pyroptotic signalingwhile ferritin handling and mitophagy status further skew redox homeostasis toward irreversible injury in EESCs