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Under physiological conditions, the antioxidant system in the body, covering antioxidant enzymes [superoxide dismutase, catalase (CAT), and glutathione (GSH) peroxidase (GPX)] and antioxidants (vitamins C and E, flavonoids, carotenoids, GSH, and micronutrients), is involved in maintaining the dynamic balance between ROS production and metabolism

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Virus supernatant was collected after 24 and 48 h and briefly centrifuged at 300 g and passed through a 0.45 m syringe

Finally it should be noted that homozygous disruption of Trx1 or TrxR1 in mouse zygotes results in severe defects in early embryonic patterning without having any detectable impacts on either the level of cellular oxidative stress or cell proliferation [49, 108, 177181]