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B12 deficiency can also lead to the destruction of immature red blood cells in the bone marrow, which can cause jaundice (yellowing of the skin and whites of the eyes)

Even though total body weights were similar on a normal chow diet, total WAT mass was reduced in HSL null mice compared to control and this difference was exaggerated on a high fat diet, with total WAT weight more than 70% lower in HSL null mice than in control