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Whats happening: New tissue has matured

April 11,2025 - Yesterday's CMS announcement that it "does not intend to approve new or extend existing requests" for Designated State Health Programs (DSHP) and Designated State Investment Programs (DSIP) funding could have significant unintended consequences for healthcare delivery and state-led innovations

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This, together with the discovery of high-affinity binding sites for [ 125 I]Ang IV in the central nervous, vascular and renal systems, 16, 116, 117 has led to the concept of a novel Ang receptor subtype: the AT 4 receptor, 14 which was convincingly shown to be insulin-regulated aminopeptidase (IRAP), a membrane-anchored zinc-dependent metallopeptidase