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For example, inhibition of pyruvate dehydrogenase dephosphorylation seems to strengthen its activity, with a concomitant reduction in the expression of fatty acid metabolism-related genes, such as muscle-type carnitine palmitoyl transferase-1 (mCPT-1) (45)

doi: 10.1038/nchembio.2238 36 DollSPronethBTyurinaYYPanziliusEKobayashiSIngoldIet al

It's an antioxidant-driven brightener that addresses overall dullness, free radical damage, and systemic pigmentation across the entire face