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In this form the sulfate of P-APS is reduced to sulfite by the free thiol (reduced) group of Sulfur Assimilation The reduced sulfur is finally transferred from the carrier to O-acetylserine (OAS) forming cysteine : O-acetylserine + H2S (or carrier-S-S-) cysteine + acetate The OAS is formed from serine and acetyl-CoA: serine + acetyl-CoA O-acetylserine + CoA This whole process is illustrated as follows: This is summarized in Fig

Indeed, the process of adaptation to glutamine deprivation weakens the response to hypoxia, which normally strongly induces the expression of glycolytic enzymes 83

A 96-well plate was used for measurement, and the standards and samples were added in sequence

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