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Data suggest that the primary heat shock transcription factor HSF-1 is not essential for celastrol-mediated protection

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For instance, Lactobacillus kefiranofaciens has been associated with the improvement of viscosity during fermentation while Leuconostoc mesenteroides is responsible in aroma formation that eventually affected the final sensory quality of kefir (Dailin et al., 2016

The further confirmation of the enhanced healing is obtained through the histopathological analysis which demonstrates the existence of organized collagen Fibers, improved angiogenesis, decrease in inflammatory infiltration, and normal tissue architecture