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Comparison of safety and tolerability with continuous (exenatide once weekly) or intermittent (exenatide twice daily) GLP-1 receptor agonism in patients with type 2 diabetes

The plasma volume changes were evaluated by using the following formula: 100 * (Hct pre /Hct post 1)/(1 Hct pre ) at time 2, time 3, and time 4 ( Randomization Study participants were randomly assigned to one of two groups using a computer-generated randomization code (CleanWeb software)