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doi: 10.4161/cc.21384 119 NigdeliogluRHamanakaRBMelitonAYOLearyEWittLJChoTet al

Int J Mol Sci 25(19):10535

Phase 2 clinical trials observed mean body weight reductions of up to 24% over 48 weeks significantly outperforming semaglutide and tirzepatide in head-to-head comparisons

The results showed that NQO1 reduced IFN- luciferase activity in response to co-transfection with poly(I:C), RIG-I, MAVS, STING, and TBK1 in a dose-dependent manner, however, there were no significant changes in IKK- mediated induction of IFN- luciferase activity after co-transfection with different doses of NQO1 (Fig