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Select microbial metabolites in the small intestinal lumen regulate vagal activity via receptor-mediated signaling

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In a meta-analysis examining the efficacy of metformin treatment for GDM, it was found that the incidence of severe neonatal hypoglycemia was significantly reduced in the metformin-treated GDM group, potentially due to improved maternal glycemic management (Nilsen et al., 2024

It is worth noting that the changes in SIRTs activity and expression are closely related to the pathophysiological processes of kidney disease, including AKI and CKD (Perico et al., 2024)