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Brain 144 , 37273741 (2021)

Without adequate L-Carnitine, the transport of these fatty acids is severely hampered, leading to a reduced capacity for fat utilization as an energy source

Immunofluorescence The following antibodies were used for detecting the respective proteins: anti-HLA (rabbit, 1:1500, Abcam, ab52922) and anti-Ki67 (rabbit, 1:1000, Fisher Scientific, RM-9106-S0)

Eledon announces positive topline results from phase 2a trial of tegoprubart demonstrating safety, target engagement, and biomarker response in patients living with amyotrophic lateral sclerosis