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Column C (Impact of Work RVU Changes): This column shows the estimated CY 2025 impact on total allowed charges of the changes in the work RVUs, including the impact of changes due to potentially misvalued codes

corroborated by Oostdyk 2024) and downregulates surface GLP-1R within 12 hours at physiological albumin (Hinds 2024), so the sustained signal held against that fade, set by dose, is what carries the effect