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The most responsible framing is: Short-term tolerability is not the same as long-term safety Manufacturing quality heavily affects risk People with medical conditions or those taking medications should talk to a clinician before considering unapproved substances

Its important to note that B12 injections are most effective for patients with a documented deficiency

Babies born to individuals who were deficient in folic acid during pregnancy may be Most people get enough B vitamins through their diet

The NHS treatment page lays it out clearly: Loading phase (no neurological symptoms): 1mg every other day for two weeks, or until symptoms stop improving