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10.1172/JCI140989 J Clin Invest

Gelardi M, Porro G, Sterlicchio B, Quaranta N, Ciprandi G, Group On Sonoring IS

SREBP-1a and SREBP-2 are the predominant isoforms of SREBP in most cultured cell lines, whereas SREBP-1c and SREBP-2 predominate in the liver and most steroidogenic tissues

EspG and VirA, along with other pathogenicity factors, are encoded within horizontally transferred genomic islands that encode additional proteins enabling pathogenicity 23,24,25