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The following comparison summarizes the key considerations: For patients with intact GI absorption, oral high-dose supplementation (1,000 to 2,000 mcg daily) provides a convenient and cost-effective path to correcting deficiency

After the acute repletion phase, therapy is usually transitioned to an oral maintenance multivitamin containing a physiological dose of pyridoxine (2-5 mg daily) for several weeks, along with dietary counseling to prevent recurrence

Vitamin B12 Vitamin B12 (cobalamin) is an essential water-soluble vitamin required for red blood cell production, DNA synthesis, and neurologic function

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