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Preman, P., Alfonso-Triguero, M., Alberdi, E., Verkhratsky, A

INPP4B inhibits glioma cell proliferation and immune escape via Inhibition of the PI3K/AKT signaling pathway

Its important to note that MK-677 per se has a modified non-peptide structure that makes it orally active, though it has a similar mechanism of action as peptide-compounds in the GHS class [27]

If you have intestinal issues, and especially if you have an inflammatory bowel disease, you may want to try cutting out foods high in ergothioneine for a period of time to see if it impacts your symptoms