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Description

TGF- also enhances glycolysis, increasing the generation of 3-phosphoglycerate (3-PG), a critical intermediate that feeds into serineglycine metabolism [108, 109]

Because of this need, the environment of the ER lumen is net-oxidizing toward its client proteins, and an inability to form disulfide bonds would be expected to dramatically compromise ER function

doi: 10.1016/j.fct.2022.113492 77 ZhouXWangFZhouRSongXXieM

Bioavailability can vary widely depending on diet-related factors including the nutrient and its form, the food matrix, and the existence of dietary antagonists limiting the absorption of the nutrient