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Acta 1758 , 9941003, (2006)

Intervention strategies fall into three categories: upstream inhibition of glycolytic enzymes (e.g., LDHA inhibitors) and lactate transporters (MCT1/4 inhibitors), direct targeting of the lactylation machinery (e.g., p300/CBP inhibitors), and combination therapies that integrate these metabolic approaches with conventional treatments ( Figure 2A )

By using this sublingual method, some research suggests it could potentially support more rapid absorption of the nutrient through mucosal tissues and bypass digestion