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In addition, in the ARDS model, ACE2 knockout mice displayed more severe symptoms of respiratory shut down compared with wild-type mice [43]

The enzymatic-mediated modulation strategy also proves to be an effective approach for realizing the regulation of the aggregation process of small molecules within cells

Example 7 In vivo immune response Humoral immune response was measured by evaluating total serum levels of IgG, IgM and IgA using methods known in the art