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JAMA Surg 159(9):1087-1089, 2024

10.1038/s41467-025-59490-y 79 HuffS

As discussed in other sections of this review, the first pass metabolism of oral products in the liver may increase inflammatory cytokines such as hsCRP and other coagulation proteins increasing risk of thrombosis in susceptible individuals (Brosnan et al., 2007