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For example, a meta-analysis of randomized controlled trials revealed that vitamin D supplementation led to a significant decrease in TPO antibody titers, suggesting a direct impact on thyroid autoimmunity ( 1.5 The potential impact of vitamin D supplementation on patient prognosis 1.5.1 Evaluation of clinical studies and supplementation effects Clinical research has increasingly focused on the role of vitamin D in modulating immune responses and its potential therapeutic effects in various autoimmune diseases, including HT

However, in EGFR-TKI (tyrosine kinase inhibitor)-tolerant NSCLC, combination therapy with -elemene and erlotinib overcomes resistance by promoting ferroptosis [129] (Table 2)