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This process involves includes many mechanisms at nanoscale (gene expression), mesoscale (changes in enzymes, ion channels, cytoskeletal proteins, receptors and secreted molecules) to macroscale (neuropathy) levels with the final common consequence of the lost retinal output to the brain (Figure 1)

A further challenge is to provide devices to different regions and potentially to rural areas without biobanking or storage and tissue preparation facilities

Role of reactive oxygen species in the defective regeneration seen in aging muscle