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Finally, low glutamine in the core region of solid tumors led to histone hypermethylation due to decreased -ketoglutarate level, resulting in cell dedifferentiation and therapeutic resistance in melanoma cells [64]

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C12) (Nimbkar et al., 2022)

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Diagnostic Value of C Reactive Protein in Infections of the Lower Respiratory Tract: Systematic Review

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In summary, oxidative stress can promote inflammation in the ovaries and cause ovarian aging (Figure 3)

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