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sgRNA complexes were synthesized by mixing equal volumes of crRNA (2 l, 160 M in nuclease-free water) and tracrRNA (2 l, 160 M) and incubated at 37 C for 30 min before Cas9 (2.7 l, 10 g l 1

The balance between these two forms is vital for maintaining cellular health

In a video posted on social media on Monday, Ms Miller admitted to lying about the diagnosis and said it came from "one stupid sentence that I deeply regret"