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This strain was susceptible to human HT-29 tumour growth comparable to the isogenic C57BL/6 RAG1 KO strain (Supplementary Fig

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Nilotinib is a tyrosine kinase c-Abl inhibitor approved for the treatment of leukemia, that has also shown to increase autophagy and degradation of intracellular -syn aggregates (Fig

326 Specifically, IFN- impedes neutrophil accumulation by downregulating the expression of CXCR2 and CXCR4 on tumor cells, thereby disrupting the binding of their corresponding ligands