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Silencing of these six genes conferred protection against erastin-induced ferroptosis (40% rescue for 6/6 hairpins), but not cell death/cytostasis induced by STS, rotenone, rapamycin, the proteasome inhibitor MG132, the DNA-damaging agent camptothecin or the CaFIG

Su TA, Shihadih DS, Cao W, Detomasi TC, Heffern MC, Jia S

Lipid aldehyde levels in CSE-depleted HeLa cells following treatment with either RSL3 (5 M) or CHP (40 M) for 4 h, as measured by CHH staining (middle panel)

Pen Dosage Chart GLP-2T 5-Amino-1MQ Slu-pp-332 MOTS-c Glutathione Dosage & Protocols Variations GLP-2T Standard Research Protocol Dose: 2.5 5 mg (variant 5 mg pen = 76152 clicks / variant 10 mg pen = 2550 clicks / variant 15 mg pen = 2550 clicks) Duration: 8 12 weeks Frequency: 1 weekly Cycle Interval: Optional 2-week pause Goal / Description: For basic metabolic modulation studies Therapeutic Research Protocol Dose: 10 15 mg (variant 15 mg pen = 100150 clicks) Duration: 24 48 weeks Frequency: 1 weekly Cycle Interval: Repeat after 1 month Goal / Description: Modeled on SURPASS/SURMOUNT designs