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10.1080/01635581.2022.2049321 Nutr Cancer

Synergistic action of sodium selenite and N-acetylcysteine in acetaminophen-induced liver damage

suggested that PTU therapy might be continued with caution in the presence of elevated liver transaminases, when no hyperbilirubinemia is present.15 However, regular monitoring of liver biochemistry has been suggested to allow discontinuation of PTU in suspected cases of hepatic injury.15,17 The diagnosis of PTU hepatotoxic effect should always be suspected in the patient receiving PTU therapy in whom clinical or biochemical evidence of acute hepatitis develops