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Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)

A narrative review concluded that the practice is controversial because there are no standardized dosing protocols and nearly onethird of patients report adverse effects, ranging from mild gastrointestinal symptoms to liver dysfunction and lifethreatening allergic reactions

Thus, therapeutic strategies targeting oxidative stress and GPX4 activity may offer effective relief for various pain syndromes

4 Calibration curves prepared using pseudo-endpoint method and kinetic method A) Calibration curve prepared using pseudo-endpoint method